True story, and frankly, whose else is sick of it?…
“Just the facts, ma’am…”
How this all relates to Clinton and the Epstein probe:
In its Jeffrey Epstein probe, the House Oversight Committee chairman sought sworn testimony and documents from Bill Clinton concerning the nature, frequency, and purpose of his contacts with Epstein, including travel records, calendars, correspondence, and any Clinton Foundation records reflecting Epstein-linked meetings or donations.
From Hillary Clinton, the committee requested testimony and records focused on institutional oversight, including whether Epstein or his associates had access to the State Department, and sought emails, visitor logs, and related records to assess how Epstein maintained elite access and whether federal agencies failed to properly scrutinize or restrict him.
None of this has been forthcoming…
Introducing a new comedy theme- Coffee Humor!
Ok. Enough of that. Things are getting a bit too personal. But while we are on the topic…..
Turning to masks once again …
I still don’t drink Bud – but it brought a tear to my eye.
On Monday, February 2, 2026, the groundhog will acknowledge the ice, stress that it is “complex,” “systemic,” and “not new,” and will assure the public that experts are aligned.
Then he must convene a task force to study it.
After six weeks of hearings, a press conference, and a strongly worded statement about equity for shadows, he concludes the future was frozen, but good news: the ice is historic, unprecedented, and someone else’s fault.
He will then go back underground to draft the narrative.
Working to control the messaging, until spring becomes a misinformation problem.
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Having spent the last two days preparing for the worst, we ended up with 2 inches of snow and some cold, wet rain…
Luckily for us, this storm was measured in “man” inches.
(However, the horrifically cold forecast for the next week is not going to be a fun time, but at least we aren’t battling one-degree temps and two feet of snow!)
FAFO
On one side, we have the Antifa radicals wanting to commit violence, even murder, against Federal officials.
Such as this perfectly normal person:
Before becoming an Antifa (or is that Trantifa?) influencer, urging others to kill ICE agents, Kyle Edward Wagner was a cross-dressing activist.
Yep.. this is the same (sane?) person…
How does one go from cross-dressing weirdo to Antifa radical – all in the name of “protecting” illegal aliens?
The left hive-mind lives in a bizarro world –
Examples of the left threatening to kill ICE agents are everywhere on social media. The violence isn’t coming from the right – let’s be clear
Some of the crazy radicals have millions of followers. One can only hope that the FBI or the DoJ will soon be knocking on their door!
(Then the question arises, why hasn’t this guy been arrested yet?)
Waiting…
On the other side are ICE officials. They are minimally trained to deal with violent crowds or SWAT team methodology (why would they be). These officials are being thrown into situations where they are being doxed, their license plates tracked, the personal information being shared with radicals like the men threatening to kill Federal officials in the video above. The well-funded, financially backed by Soros left has even built apps to follow and track ICE agents.
Ice agents are minimally trained in how to deal with crowds of people threatening them with guns, throwing rocks, screaming, etc. How do ICE agents train for online videos that promote killing Federal ICE agents?
This is the type of behavior that these agents have to cope with.
These are actual cannibals „protesting” on the streets of Minneapolis. Authorities forced the perpetrator to cough up the remains of the finger, but it appears to be too damaged to be reattached.
BTW- this is all being planned and coordinated from the top levels of NGOs run by democrat party leaders and Soros.
City and state officials in MN, rather than cooperating with Federal officials to help find ILLEGAL aliens, are working to cause riots and mayhem. They are encouraging violence and mob action.
Under President Trump, illegal aliens are being given due process while being housed in Federal buildings before being deported. What a shock- under President Trump, ILLEGAL aliens aren’t just being released back into communities.
Did you know that under past presidents, illegals would be arrested and “processed” – that is, they would be assigned their own personal attorney, who would then schedule a court date -often years in advance, and these illegals would be RELEASED back onto the streets. Only to disappear from the system again. Rinse and repeat. They have been trained not to carry ID, don’t admit to which country they came from, and basically, were allowed to re-enter the USA to live as they please.
Well, times have changed.
My support and prayers go out to those brave ICE agents who are having to put up with so much abuse and harassment.
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Never forget – the real slavery these days is debt.
Between Gov. Spanberger’s executive actions on day one of her term this week and the bills being presented by the completely blue-dominated legislators in both the state House of Representatives and Senate, Californication is coming at Virginia fast!
As we all watch Virginia descend into an evil maelstrom of Marxist pro-criminality, please allow me to explain what happened and what the remedy is.
Think back to 2024. One of the major reasons the American people elected Donald Trump was so he would fulfill his campaign promise of reducing the size, scope and power of the evil Leviathan housed in the federal administrative state that controls our daily lives in a grotesquely unconstitutional manner.
This necessarily meant greatly reducing the number of federal civilian employees.
As someone who has spent many years in military uniform supervising civilian federal employees, I can assure you that 95% of those civil service employees completely and utterly disregard the fact that their boss is the American electorate.
So when the American electorate says “We think your job equals tyranny and we don’t want you employed in that job anymore,” instead of recognizing that the only people entitled to make this decision are the American voters, they resist, thinking that they are somehow more important than the Constitution and the electorate.
It just so happens that the great majority of these unrepentant federal workers reside in Northern Virginia. So when Trump did what the American people wanted him to do and he fired so many of these unneeded leeches, those unionized leeches decided to vote Democrat at all costs, as a matter of preserving their wholly unnecessary jobs and cushy livelihoods.
Another key fact is that the suburban areas of Northern Virginia like Fairfax and Loudon Counties control state-wide elections, and federal workers control those counties. So the inevitable happened and those unneeded, rent-seeking federal workers swung control of Virginia to Democrats.
And guess what? Those elected Democrats took opposition to reducing the size of the federal government as a mandate to rapidly enact an Orwellian set of laws that would make Karl Marx and Che Guevara blush: outrageous taxation; elimination of basic human rights like those embodied in the Second Amendment; pro-illegal alien policies; refusal to enforce federal immigration laws; draconian rules mandating that confused children can destroy their genitals without parental consent; laws supporting criminality; and a host of other insane laws and policies designed to turn Virginia into a modern version of Ingsoc.
Who is to blame for this evil? Federal workers. Their refusal to acknowledge the will of their boss (i.e., YOU, the American voter) has tossed an entire state into Marxist despair. The ability of federal civil “servants” to cling to their cushy, unneeded jobs is why Virginia has become an un-American hellscape overnight. They simply DO NOT CARE that their fellow Americans are condemned to live in crime and tyranny, because that preserves their cushy sinecures. They are not civil “servants.” They are civil MASTERS, and they don’t care what you think.
Place the blame where it belongs. Federal workers did this to you, Virginia. THEY are to blame.
But there are two ways Trump can remedy this dire state of affairs:
1. Keep on cutting the bloated federal Leviathan.
2. Move federal agencies out of DC and spread them across the rest of the country, depriving this unionized cabal of unelected bureaucratic tyrants of the nefarious power of concentration.
I have a message for Virginia (less Fairfax and Loudon Counties): the rest of America is here to save you. Hold fast, don’t give up, and we WILL eventually save you from this tyranny.
MAGA. MVGA.
Immigration and Customs Enforcement (Urząd Imigracyjny i Celny), zajmującą się egzekwowaniem prawa imigracyjnego i celnego, oraz międzynarodowy skrót In Case of Emergency
I went to the grocery store yesterday morning… Seriously? The shelves were already emptied of staples.
The storm coming our way is bad, but the ice storm following is going to knock out lots of power. Then what is worse is the temps falling to 1 degree at night and not going above freezing during the day for as long as they can forecast out. With nighttime temps ranging from one to ten degrees night after night. Stock tanks soon become blocks of ice.
In Virginia, our waterlines and back-up systems aren’t built to withstand these temperatures.
So stay tuned – lots of whining is forecast for the coming weeks.
China’s Organ Harvesting Industry and the True Nature of America’s Biggest Adversary
Author: JAN JEKIELEK
Introduction
The existence and normalization of forced organ harvesting from living donors is a hard thing for anyone raised on Judeo-Christian ethics to confront, let alone those trained in the medical bioethics developed since the Nuremberg trials. In this book, author and Epoch Times Washington Bureau Chief Jan Jekielek, famous for the “American Thought Leader” interview series, slowly and carefully walks the reader down a path paved with specific examples, making it impossible to look away and avoid the truth of the crimes against humanity that have been normalized by the Central Communist Party of China (CCP).
But that is really just the prelude, a point of entry to the central journey that forms the backbone of this book. By examining this specific set of crimes, the creeping complicity of the western transplant community and the academic and pharmaceutical industry that has enabled them, Jekielek reveals the intentional weaponization of corrupt practices by the CCP as one key component of its policy of unrestricted warfare against the United States, the ultimate consequences of utilitarian ethics applied to public health, and the hidden hand of the CCP in advancing globalist policies by the World Health Organization.
The work starts out by focusing on the horrors of organ harvesting, but the real reason this is a must-read is the moral, logical, and political clarity of its critique of the naïve, corrupt bargain lying at the heart of Kissinger’s China doctrine.
“Killed to Order”, set for publication by Skyhorse and currently available for pre-order on Amazon, exposes the Chinese Communist Party’s (CCP) forced organ harvesting industry. The book draws on survivor testimonies, evidence, and analysis to argue that the CCP systematically murders prisoners of conscience—primarily Falun Gong practitioners, but also Uyghurs, Tibetans, and Christians—for organs on demand, serving both as persecution and a profit-driven tool for elite longevity.
Structured in two parts, the book first details the history, mechanisms, and evidence of this “new form of evil” under communism, including how the CCP instrumentalizes society and makes complicity widespread. The second part explores global implications, such as unrestricted warfare, transnational corruption, and why the U.S. must confront China as its greatest adversary.
The prologue illustrates the issue through a fictionalized story of a Western patient unwittingly benefiting from a “China option” transplant, later realizing its horrific source. Initial reviews include praise from human rights experts, historians, and China analysts, emphasizing the book’s role in highlighting ongoing atrocities and calling for action.
The book opens with Jekielek’s personal journey into the issue, sparked by a 2006 rumor of a secret concentration camp in Sujiatun, China, where Falun Gong practitioners were allegedly held for organ extraction. He interviews “Annie,” the ex-wife of a neurosurgeon involved in the operations, who describes an underground facility holding thousands for live harvesting. Corneas, kidneys, livers, and skin are removed from living victims, with bodies incinerated to erase evidence. A veteran military doctor corroborates this, revealing 36 similar camps across China, treating detainees as “economic assets.” The prologue sets the tone: this is an industrial-scale “kill-to-order” system enabled by the CCP’s persecution of Falun Gong since 1999, when Jiang Zemin labeled it an “evil cult” and vowed its elimination. Jekielek highlights the psychological barrier to believing such horrors, drawing parallels to Holocaust denial, and introduces the “China option” as a euphemism for sourcing organs from prisoners of conscience.
The prologue to Killed to Order frames the horror of forced organ harvesting from the living by placing the reader into the lived reality of the thousands of Western patients facing the grim reality of modern organ matching lotteries. With empathy, the author walks us through the logic of medical tourism-based transplantation, and then introduces readers to the horror of the epiphany that the seemingly miraculous abilities of Chinese transplantation centers to acquire recipient-matched organs depend on maintaining a population of captive living human beings to be organ harvested on demand. It then reveals an even darker underlying reality; having developed this capability and infrastructure, China’s ruling party is now exploiting prisoner organs to advance the lifespan of aged oligarchs. The author’s overall assessment is both starkly blunt and deeply humanitarian, and sets up the body of the work:
There are still many unanswered questions about China’s forced organ harvesting industry. Questions with grave implications for the future of medicine, the future of morality, and the future of the free world. But thanks to the tireless work of investigators, reporters, and unbelievably courageous Chinese whistleblowers, we know far more than we did two decades ago. We know for certain that Falun Gong, Uyghurs, and other groups are still being targeted. We know that the Chinese Communist Party will stop at nothing to ensure its own survival. And we know that Western elites and Western media are being steadily co-opted—made complicit in the CCP’s crimes against humanity.
At the end of the day, that is what this is: a crime against humanity, and we must not allow ourselves to forget the human element.
The body of the text is divided into two sections: Part I: A New Form of Evil, and Part II: The Global Implications of China’s Forced Organ Harvesting Industry.
Part I: A New Form of Evil
Part I of “Killed to Order,” titled “A New Form of Evil,” exposes the Chinese Communist Party’s (CCP) systematic forced organ harvesting as an industrialized form of genocide rooted in totalitarian control. Beginning with whistleblower accounts like “Annie’s” revelations of secret camps where Falun Gong practitioners are held for live organ extraction, it traces the CCP’s long history of mass killings under Mao and beyond, illustrating how the regime instrumentalizes healthcare, law enforcement, and society to dehumanize and exploit targeted groups such as Falun Gong adherents, Uyghurs, Tibetans, and Christians. Through survivor testimonies, like Cheng Pei Ming’s harrowing escape after partial organ removals, and a timeline of mounting evidence from reports like Kilgour-Matas and the China Tribunal, the section analyzes why communist systems—especially the CCP’s “regionally administered totalitarianism”—foster such horrors by prioritizing Party supremacy, incentivizing complicity, and viewing human lives as resources for profit and elite longevity.
Chapter 1: A Rumor Is So Extreme It’s Hard to Believe This chapter delves into the initial investigations following the Sujiatun allegations. Jekielek recounts early reports from The Epoch Times, including Annie’s testimony about her husband’s role in removing corneas from living Falun Gong practitioners. The facility reportedly held up to 6,000 detainees at its peak, with medical teams conducting compatibility tests and providing minimal sustenance to keep organs viable. Bodies were incinerated on-site. A second whistleblower, a military doctor from Shenyang, describes a network of camps where executions are botched to allow live extractions, and families receive fake ashes. The chapter explores the psychological denial of such atrocities, comparing it to initial skepticism about the Holocaust, and introduces key investigators like David Kilgour and David Matas, who later confirm the rumors through their 2006 report.
Chapter 2: A Long History of Killing Jekielek traces the CCP’s history of mass killing, from Mao’s Great Leap Forward (1958-1962), which caused 45 million deaths through famine and executions, to the Cultural Revolution (1966-1976), where ideological purges killed millions. The chapter argues that forced organ harvesting is a continuation of this pattern, evolving from political campaigns to industrialized murder for profit. It highlights how the Party’s utilitarian ethic—where individual lives are subordinate to collective goals—enabled such systems, with early organ extractions from executed prisoners dating back to the 1980s.
Chapter 3: The CCP Instrumentalizes Everything Here, the focus is on the CCP’s total control over society, where every institution serves Party ends. The chapter discusses the “610 Office,” created in 1999 to eradicate Falun Gong, coordinating arrests, torture, and organ harvesting. It explains how the regime instrumentalizes healthcare, turning hospitals into extensions of state repression. Blood tests and medical exams in detention centers are not for health but for organ matching, creating a “living organ bank.” The system profits hospitals, doctors, and officials, with transplants generating billions.
Chapter 4: What Targeting Falun Gong Reveals about the Nature of the CCP Falun Gong, a spiritual practice blending qigong exercises with moral teachings of truthfulness, compassion, and forbearance, grew to 100 million practitioners by 1999, alarming the CCP. Jiang Zemin saw it as a threat to Party supremacy, labeling it an “evil cult” and launching a genocide. The chapter reveals how the persecution provided a “supply” for organ harvesting: practitioners’ healthy lifestyles (no smoking, drinking) made them ideal donors. It details torture methods to force renunciation, and how refusals led to organ extraction. Experts like Ethan Gutmann estimate 65,000-100,000 deaths annually.
Chapter 5: The Evidence and the Road to Get There This is the evidentiary core, chronicling two decades of proof. It opens with Cheng Pei Ming’s story, the first known survivor: arrested for practicing Falun Gong, he was tortured, blood-tested, and operated on without consent in 2004 and 2006, losing part of his liver and lung. He escaped and confirmed the removals in the US in 2020. The chapter lists a timeline of evidence: 1984 regulations allowing prisoner organ use; 1994 Uyghur extractions; 2005 short wait times for hearts; 2006 Sujiatun revelations and Kilgour-Matas report; 2009 “Bloody Harvest” book estimating 40,000+ transplants; 2012 “State Organs” essays; 2014 “The Slaughter” by Ethan Gutmann (65,000 deaths); 2016 update projecting 60,000-100,000 annual transplants; 2017 Korean hidden camera exposé; 2018 COHRC report on hidden volumes; 2020 China Tribunal judgment of crimes against humanity; 2021 UN experts alarmed; 2022 GRC advisory; 2024 DAFOH report; 2025 Robertson thesis on “extractive repression”; and more. It emphasizes falsified data, short waits, and whistleblowers.
Chapter 6: Why Communist Systems—and the CCP in Particular—Enable Forced Organ Harvesting Communist systems, especially the CCP’s “regionally administered totalitarianism” (RADT), incentivize atrocities through top-down directives and local competition. The chapter draws on experts like Chenggang Xu (RADT model), Harrison Koehli (pathocracy and “ponerization,” where psychopaths rise), and John Lenczowski (operational communism over belief). The CCP dehumanizes groups like Falun Gong, enabling mass incarceration, database building, and kill-to-order harvesting. It discusses how the system expanded to infants via surrogacy and state seizures, and how Western media shifted post-2001 Jiang Zemin interview to echo “cult” rhetoric.
Chapter 7: Make Everyone Complicit—Including Your Adversaries The CCP’s “rob, replicate, replace” model exploits Western greed, capturing elites through economic entanglement. The chapter critiques the Kissinger Doctrine for enabling China’s rise, detailing how US financial elites listed state-owned enterprises with minimal oversight, leading to $7-12 trillion in transfers. It argues the CCP wages “people’s war” via fentanyl, elite co-option, and moral compromise, making adversaries complicit in its crimes.
Part II: The Global Implications of China’s Forced Organ Harvesting Industry
Part II of “Killed to Order,” titled “The Global Implications of China’s Forced Organ Harvesting Industry,” examines how the Chinese Communist Party’s (CCP) organ harvesting atrocities reveal its broader strategy for global dominance, viewing the United States as a zero-sum adversary in an era of “unrestricted warfare” that weaponizes economics, psychology, law, and technology through tactics like the “Three Warfares” and the United Front Work Department as a “magic weapon” for co-opting elites, suppressing dissent transnationally, and corrupting institutions such as the WHO. It critiques America’s “fatal attraction” to the CCP through misguided policies like the Kissinger Doctrine, which enabled economic entanglement and moral compromise, while exploring opportunities for internal change in China via movements like Tui Dang and urging legislative actions, such as U.S. bans on organ tourism and international tribunals, to combat these evils and prevent the erosion of Western values.
Chapter 8: Zero Sum—How the CCP Perceives America The CCP views the US as its primary adversary in a zero-sum world, pursuing dominance via “Unrestricted Warfare” and “Gross National Power.” Drawing on Pillsbury’s “The Hundred-Year Marathon,” it details covert strategies to weaken America through trade, technology theft, and ideological subversion.
Chapter 9: Unrestricted Warfare (and The Three Warfares) “Unrestricted Warfare” doctrine weaponizes everything—cyber, economic, legal, psychological. The “Three Warfares” (public opinion, psychological, legal) are detailed, with examples like TikTok as psychological warfare and WTO manipulation as legal warfare. Military-civil fusion ensures civilian tech serves military ends, e.g., Wuhan lab research.
Chapter 10: The Magic Weapon The United Front Work Department (UFWD) co-opts elites, diaspora, and institutions. It details “Chinese police stations,” transnational repression against Falun Gong media like The Epoch Times and Shen Yun, and smear tactics against survivors like Cheng Pei Ming.
Chapter 11: Transnational Cooperation, Corruption, and Coercion The CCP influences global bodies like the WHO, exploiting shared technocratic views. It details Huang Jiefu’s partnerships with TTS and Vatican endorsement, enabling abuses. Western complicity in transplants normalizes CCP ethics.
Chapter 12: Fatal Attraction: How the US Perceives the CCP The US misperceived the CCP as reformable, financing its rise via Kissinger Doctrine. Theories like Smith’s “Thirty Tyrants” argue elites were captured. Decoupling trade from human rights empowered the regime, leading to dependencies in rare earths, medicine, and more.
Chapter 13: Opportunity for People in China? Change from within is hard due to totalitarianism. The Tui Dang movement—over 455 million renunciations—offers quiet dissent. China’s middle class erodes amid property collapse and inequality, weakening the regime’s “prosperity for compliance” pact.
Chapter 14: Legislating Against Evil Six US states ban reimbursing China transplants; federal bills like Falun Gong Protection Act and Stop Forced Organ Harvesting Act advance. Institutional reforms (e.g., HHS penalties) and legal theories (e.g., prosecuting organ tourism) offer paths forward. Grassroots action is key.
Epilogue: It’s Not Too Late
Jekielek distinguishes the CCP from Chinese people and culture, arguing the Party’s crimes are anti-China. He warns CCP ethics erode Western morals via medically assisted death and loosened donor rules. The epilogue calls for recovering moral clarity to counter communism’s advance, emphasizing it’s not too late to act.
In Summary
In Killed to Order: China’s Organ Harvesting Industry and the True Nature of America’s Biggest Adversary, Jan Jekielek delivers a searing, meticulously documented indictment of one of the most horrifying crimes of our era: the Chinese Communist Party’s systematic, state-sponsored forced organ harvesting from prisoners of conscience, primarily Falun Gong practitioners, but extending to Uyghurs, Tibetans, Christians, and others.
Through survivor testimonies like that of Cheng Pei Ming—the first confirmed survivor of partial live organ removal—whistleblower accounts, a comprehensive timeline of evidence spanning two decades (from the 2006 Sujiatun revelations to the 2020 China Tribunal judgment and beyond), and incisive analysis of CCP ideology and global strategy, Jekielek transforms what many once dismissed as an “unbelievable rumor” into an undeniable reality.
What elevates this book beyond mere exposé is its bold framing: forced organ harvesting is not an isolated atrocity but the ultimate lens through which to understand the CCP’s true nature—its dehumanizing utilitarianism, total instrumentalization of society, and zero-sum worldview that treats human lives as disposable commodities for elite profit, longevity, and power. In Part I, Jekielek unflinchingly traces the historical precedents of communist mass killing and explains why such systems enable industrialized murder on demand. Part II expands the scope masterfully, revealing how the regime’s “unrestricted warfare,” United Front co-option, and transnational corruption have entangled the West, making adversaries complicit while eroding moral clarity.
Compelling, urgent, and unflinching, Killed to Order stands as a vital wake-up call, blending rigorous journalism with moral urgency. It challenges readers—especially in the free world—to confront uncomfortable truths, reject normalization of the CCP, and support legislative and ethical countermeasures before these horrors further metastasize.
In an age of moral relativism and geopolitical complacency, Jekielek’s work is essential reading: a beacon of truth that reminds us it is not too late to act, but the window is closing. Highly recommended for anyone concerned with human rights, global security, and the defense of fundamental human dignity.
We recently watched an excellent documentary on Iran. The first two episodes on the history up to the 20th century are particularly good, and would be excellent as a primer on Persia for older children. We thoroughly enjoyed watching it and highly recommend. Family friendly. The last episode gets a bit woke though.
( An image of the series is below – we found it on Amazon and the BBC channel):
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Estimates of widespread weight loss (around 25 pounds per person) are tied to the prolonged economic and food crisis during Maduro’s illegal reign.
Liberals took to the streets of New York, Chicago, Philadelphia, Washington, and other “blue zones” around the USA as well as the world, to protest the capture of Maduro.
The Democratic Party is defending a ruthless narco dictator, whose reign is known for its massive oppression and starvation. These liberals are protesting for his return to power.
Make it make sense. One day, the Democrats hold “No Kings” rallies; the next, they hold “More Kings” rallies.
The Democratic Party is approaching national political irrelevance.
In the meantime, millions of Venezuelan migrants in the USA and around the world are celebrating in the streets because of the removal of Nicolás Maduro from power.
They’re here…
Personally, I am more than a little disappointed in the statements from Rep. Massie and Rep. MTG regarding the capture of Maduro.
Lots can still go wrong with President Trump’s strategy.
But here is the thing about Trump. He is a master negotiator, and Marco Rubio has turned into one of the best statesmen we have. Together, they can turn the decades-long disaster that is Venezuela into another success story.
Don’t forget, Maduro has given three of our biggest enemies a stronghold in South America. But don’t take my word for it:
China, Russia, and Iran each play distinct but complementary roles in sustaining Venezuela. China has been the regime’s financial backbone, providing tens of billions of dollars in loans repaid with oil, along with telecommunications and surveillance systems that help maintain internal control; today, its role is more cautious and transactional, focused on recovering value rather than ideology.
Russia serves as the key political and military guarantor, offering security cooperation, intelligence support, and diplomatic shielding that helps keep Nicolás Maduro in power during moments of acute legitimacy crisis.
Iran, meanwhile, functions as a sanctions-evasion and operational partner, supplying fuel, refinery expertise, and illicit trade networks that allow Venezuela to keep its energy system running despite international restrictions.
Together, China keeps the state solvent, Russia keeps the regime standing, and Iran keeps the system functioning under sanctions.
Chat-GPT
The thought of China, Russia, and Iran having a stronghold on our southern doorstep should make anyone pause…
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“If they can get you asking the wrong questions, they don’t have to worry about answers.”
― Thomas Pynchon
“Strange how paranoia can link up with reality now and then.” ― Philip K. Dick, A Scanner Darkly
True story, that…
“If you would know who controls you, see who you may not criticize.” ― Tacitus
“Paranoia is just having the right information.” ― William S. Burroughs
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The biggest news in the nation this week, received almost no coverage…
Livelihoods were destroyed. Patriots were unjustly imprisoned, fined millions, disbarred, and labeled “insurrectionists” for protesting what is now acknowledged as the truth: that the 2020 election was indeed stolen.
249 years ago to the day, this happened:
What’s a few more Christmas jokes among friends?
The Amish Christmas lights were spectacular this year!
No words can actually describe the message of this video:
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The Limited Hangout: Blame Congress for the Epstein mess- they passed the bill where the government could redact whatever the heck they wanted – to protect the government. Now, the public will never know how involved our government (IC) or foreign governments were in setting up honey pots, blackmailing politicians, business people, and government officials, etc. Congress knew exactly what would happen. Including those who are now screaming the loudest – and who also happened to be the same Congresscritters who put in the amendments that the government could redact whatever they wanted – as long as they redact in ways that are in the government’s interest. Congress was protecting their own in doing what they did. Now they can blame the DoJ for redacting and pat themselves on the back for doing the right thing by passing this bill.
Don’t be fooled. It is total BS. They set this up. Don’t blame Bondi for doing what Congress asked for.
Yeah – still funny.
The fact is that the “rainbow” flag symbolizing LGBT people is a way to attract and groom children. The flag and colors have bright, saturated colors, a simple geometric design, and rainbow imagery – imagery that is also used in many cartoons and picture books, so a CHAT-GPT query is in order:
Can you name cartoons that use the rainbow and why?
Note the pattern…
LGBT-affiliated groups and individuals intentionally place pride symbols in child-focused environments, including events like drag Queen Story Hour, cartoons, animation, and gay pride parades.
This is not age-appropriate inclusion and is most definitely ideological marketing – to children, who are at an age where fetishes can develop.
To learn more about the development of fetishes in young children, please read my essay:
This is just as true in 2026 as it was in 2017- when Branco first penned it…
For some reason, Joe Biden has raised only a small fraction of the funds needed to construct a presidential library…
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CHAT-GPT wants you to know: There is no public confirmation that Dr. Rachel Levine has undergone a “full sex-change operation” and that there has been any not publicly disclosed details of any medical or surgical procedures, and such information is considered private medical information.
Isn’t CHAPT-GPT helpful!
[jeśli potkniesz się]
Is this a true story?
(Although honestly – I can see how some might think that)
It seems fitting to add a bit of seriousness. I discussed the alum adjuvants in vaccines during a recent MAHA Action Zoom call.
I stand by these words (don’t worry, it is only a minute long):
“Now there’s another thing I want to highlight that I mentioned in the ACIP meeting, and that is that we do have the indication that we may have cumulative toxicity.”
“What I was talking about is that a vast majority of these childhood vaccines rely on a substance to make them immunogenic. What is that substance? It’s aluminum salts.”
“Are aluminum salts toxic? Yes, they are.”
“It’s a question of dose, just like everything in medicine.”
“The vaccines that our children receive have been tested without adequate controls only as individual vaccines.”
“And because our children are getting so many different vaccines, they’re getting many doses of this toxic material.”
“That has to be reevaluated.”
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On Monday, the publisher of the “Franklin the Turtle” children’s book series issued a response after Defense Secretary Pete Hegseth shared a depiction of the “beloved” character that the left-wing media police labeled as “violent” on X.
US Secretary of War Hegseth shared the post on Sunday, saying, “For your Christmas wish list.” This provoked howls of outrage from the lefties – including from the publisher of the Franklin Book series.
“Franklin the Turtle is a beloved Canadian icon who has inspired generations of children and stands for kindness, empathy, and inclusivity,” Kids Can Press, the series publisher, wrote online. “We strongly condemn any denigrating, violent, or unauthorized use of Franklin’s name or image, which directly contradicts these values.”
Because these are now newsworthy and worthy of a comedic skit, the Franklin images above are for educational purposes only.
<Senator Blumenthal – these memes examine a cultural phenomenon and do not promote violence. These “violent” images do not represent the views of the US government or malone.news.>
MAHA gets rightly ‘blamed’ <insert sarcasm> for Trump winning the Presidential election, but I have to say…
The Vance/Walz debate was awesome.
So, I do believe that VP Vance also deserves some credit for Trump’s reelection.
Vance, as VP, has proven to be a brilliant choice!
„J.B. is arguably the world’s most thoughtful, sophisticated, knowledgeable, and indefatigable activist for children’s health.” – RFK, Jr.
J.B. Handley is the proud father of a child with Autism. He spent his career in the private equity industry and received his undergraduate degree with honors from Stanford University. His first book, How to End the Autism Epidemic, was published in September 2018. The book has sold more than 75,000 copies, was an NPD Bookscan and Publisher’s Weekly Bestseller, broke the Top 40 on Amazon, and has more than 1,000 Five-star reviews. Mr. Handley and his nonspeaking son are also the authors of Underestimated: An Autism Miracle and co-produced the film SPELLERS, available now on YouTube.
ATLANTA, Georgia—Yesterday, something happened that has never happened in the history of American public health: ACIP voted 8-3 to un-recommend the universal birth dose of hepatitis B for babies born to mothers who test negative for the virus. After 34 years of jabbing every American newborn within hours of taking their first breath—regardless of whether their mother had hepatitis B—the committee finally acknowledged what 25 European countries figured out decades ago: it doesn’t make sense.
But watching this vote unfold, I couldn’t help but notice the absurdity of the debate itself. Committee members who opposed the change kept saying variations of the same thing: “We’ve heard ‘do no harm’ as a moral imperative. We are doing harm by changing this wording.” Another said “no rational science has been presented” to support the change.
How to End the Autism Epidemic is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.
And therein lies the fundamental problem with ACIP—and with the entire vaccine regulatory apparatus in America. They literally cannot weigh risk versus benefit because they only have data on one side of the scale.
The Missing Side of the Ledger
When ACIP debates adding or removing a vaccine from the schedule, they can produce endless data on disease incidence. They can show you charts demonstrating how hepatitis B cases in infants dropped from thousands to single digits after 1991. They can model projected infections if vaccination rates decline. They have this data at their fingertips because tracking infectious disease is something our public health apparatus actually does.
But ask them to produce equivalent data on vaccine injury, and you’ll get silence. Not “the data shows injuries are rare.” Not “here’s our comprehensive tracking of adverse events.” Just… nothing. A void where information should be.
This is not an accident. This is by design.
The safety trials for Engerix-B and Recombivax HB—the two hepatitis B vaccines given to American newborns—monitored adverse events for four to five days after injection. That’s it. If your baby developed seizures on day six, or regressed into autism over the following months, or developed autoimmune disease in the following year—none of that would appear in the pre-licensure safety data.
And the post-market surveillance? VAERS is a voluntary reporting system that the CDC itself acknowledges captures only a tiny fraction of adverse events. A Harvard-funded study found it captures perhaps 1% of actual vaccine injuries. Vaccine court has paid out over $5 billion in claims while simultaneously being structured to make filing nearly impossible for average families.
So when Dr. Cody Meissner voted against removing the Hep B birth dose and said he saw “clear evidence of the benefits” but “not the harms,” he was accidentally revealing the entire rotten structure. Of course he doesn’t see the harms. Nobody is systematically looking for them.
The Invisibility of Vaccine Injury
Here’s what most people don’t understand about vaccine injury: it’s nothing like a gunshot wound.
If you shoot someone, the cause is obvious. There’s a bullet, a wound, blood, a clear mechanism of action visible to any observer. Even a medical examiner who’s never seen the victim before can determine cause of death.
Vaccine injury doesn’t work that way. When aluminum nanoparticles from a vaccine cross the blood-brain barrier via macrophages, when they lodge in brain tissue and trigger chronic neuroinflammation, when a child slowly regresses over weeks or months—there’s no bullet. There’s no smoking gun. There’s just a before and an after, and a desperate parent trying to explain to doctors that something changed.
This invisibility is the vaccine program’s greatest protection. Because the injury mechanism is complex and delayed, because it doesn’t leave an obvious wound, because it requires actually looking to find—and because no one in authority is looking—the injuries simply don’t exist in the official record.
I watched my own son Jamie regress after his vaccines. A healthy, developing toddler who lost his words, stopped making eye contact, and retreated into a world we couldn’t reach. My wife and I know what happened. Thousands of other parents know the same thing happened to their children. But because this type of injury doesn’t show up on a simple blood test, because there’s no autopsy finding that says “vaccine-induced encephalopathy,” ACIP members can sit in a room and say with straight faces that they don’t see evidence of harm.
They’re not lying. They literally can’t see it. Because no one is measuring it.
The Chicken Pox Conundrum
Here’s an example that illustrates the insanity of our current approach.
The varicella (chicken pox) vaccine was added to the schedule in 1995. It definitely reduces chicken pox cases. The data is clear on that front. Mission accomplished, right?
But what about the other side of the ledger?
Emerging research suggests that wild chicken pox infection provides some protective effect against brain cancers—particularly glioma, the most common type of primary brain tumor. Multiple studies have found that people who had chicken pox as children have significantly lower rates of brain cancer later in life. The hypothesis is that the immune response to wild varicella provides lasting immunological benefits that extend far beyond preventing itchy spots.
Meanwhile, the vaccine itself has been associated with increased rates of autoimmune conditions. Studies have linked varicella vaccination to higher rates of herpes zoster (shingles) outbreaks in younger age groups, to autoimmune disorders, to various adverse events that weren’t captured in the original short-term safety trials.
So what’s the true risk-benefit of the chicken pox vaccine? Does preventing a week of itchy discomfort in childhood justify potentially increased rates of brain cancer and autoimmune disease later in life?
ACIP can’t answer this question. They literally don’t have the data. They can show you chicken pox cases going down. They cannot show you a comprehensive analysis of long-term neurological and immunological outcomes in vaccinated versus unvaccinated populations, because that study has never been done.
And so they keep recommending the vaccine based on the only data they have—the disease prevention data—while remaining willfully blind to consequences they’ve never bothered to measure.
The ACIP Paradox
Yesterday’s vote was historic, but it also revealed the fundamental paradox of vaccine regulation in America.
The committee members who voted to remove the universal Hep B birth dose recommendation did so largely based on comparative evidence from Europe, parental concerns, and the basic logic that vaccinating a 12-hour-old baby for a sexually transmitted disease their mother doesn’t have makes no medical sense. They were right to do so.
But the committee members who voted against the change weren’t wrong either, from their perspective. They looked at the only data they have—disease prevention data—and concluded that removing the recommendation could lead to more hepatitis B cases. And within their limited framework, they’re correct.
The problem is the framework itself.
True risk-benefit analysis requires data on both risks AND benefits. ACIP has comprehensive data on benefits (disease prevention) and virtually no data on risks (vaccine injury). So every decision they make is fundamentally flawed from the start.
When Dr. Joseph Hibbeln complained that “no rational science has been presented” to support changing the recommendations, he was inadvertently indicting the entire system. Of course no comprehensive vaccine injury data was presented—such data doesn’t exist because no one has been willing to collect it.
This is like asking someone to make an informed financial decision while only showing them potential profits and hiding all possible losses. Of course the decision will be skewed. Of course you’ll end up with a bloated portfolio of high-risk investments that look great on paper.
The Real Reform
If RFK Jr. and the new HHS leadership want to actually fix the vaccine program, they need to understand that removing individual vaccines or making them “optional” is just rearranging deck chairs on the Titanic.
The real reform is creating the data infrastructure that should have existed from the beginning.
We need a comprehensive, long-term, vaccinated-versus-unvaccinated health outcomes study. Not a five-day safety trial. A multi-decade tracking of neurological, immunological, and developmental outcomes across populations with varying vaccination status. Florida just eliminated all vaccine mandates—that state alone could provide the data we need within ten years if someone had the courage to actually collect it.
We need a vaccine injury surveillance system that actually captures adverse events. Not a voluntary reporting system that misses 99% of injuries. An active surveillance system with trained clinicians looking for the kinds of delayed, complex injuries that vaccines actually cause.
We need accountability for manufacturers. The 1986 National Childhood Vaccine Injury Act removed all liability from vaccine makers—and predictably, the vaccine schedule exploded afterward while safety research stagnated. Why would any company invest in safety when they can’t be sued for injuries?
Without this data, every ACIP meeting will be the same performance we watched this week: members confidently citing disease prevention data while admitting they can’t see evidence of harm—not because harm doesn’t exist, but because no one is looking for it.
What Comes Next
Yesterday’s vote was a crack in the wall. For the first time, an American regulatory body acknowledged that perhaps vaccinating every newborn within hours of birth for a disease primarily transmitted through sex and IV drug use doesn’t make sense when the mother has already tested negative.
But the forces of institutional inertia are already mobilizing. The American Academy of Pediatrics is “disappointed.” The American Medical Association is calling for the CDC to reject the recommendation. The pharmaceutical industry—which collects over $225 million annually from Hep B birth doses alone—will fight to restore the universal recommendation.
They will cite the same data they always cite: disease prevention data. Cases prevented. Infections avoided. Lives saved—theoretically.
They will not cite vaccine injury data, because that data doesn’t exist in any comprehensive form. They will not present long-term health outcomes in vaccinated versus unvaccinated children, because those studies have been actively avoided for decades. They will not acknowledge the thousands of families who have watched their children regress after vaccination, because those injuries aren’t captured in any official database.
And this is why ACIP will always be hamstrung. Until we build the data infrastructure to actually measure vaccine injury—to put real numbers on the other side of the ledger—every vaccine decision will be based on incomplete information. Every “risk-benefit analysis” will be a fraud, because we’re only measuring half the equation.
The hepatitis B birth dose vote was a small victory. But the larger battle—for actual science, for complete data, for true informed consent—that battle is just beginning.
And until we win it, ACIP will continue making decisions in the dark, confidently citing evidence of benefits while remaining deliberately blind to the harms they’ve never bothered to measure.
About the author
J.B. Handley is the proud father of a child with Autism. He spent his career in the private equity industry and received his undergraduate degree with honors from Stanford University. His first book, How to End the Autism Epidemic, was published in September 2018. The book has sold more than 75,000 copies, was an NPD Bookscan and Publisher’s Weekly Bestseller, broke the Top 40 on Amazon, and has more than 1,000 Five-star reviews. Mr. Handley and his nonspeaking son are also the authors of Underestimated: An Autism Miracle and co-produced the film SPELLERS, available now on YouTube.
The European Commission fined Elon Musk’s X Platform €120 million ($140 million) on December 5, 2025, for not following transparency rules under the Digital Services Act (DSA).
The main complaints were:
Deceptive Blue Checkmarks: X’s policy of selling blue verification badges for $8/month (via X Premium) without rigorous identity checks. This accounted for €45 million of the fine. It is important that the EU track each and every user for non-PC speech
Inadequate Advertising Repository: X failed to maintain a transparent database of ads, including details on payers, targeting, and content.
Restricted Data Access for Researchers: X did not provide adequate access to public platform data, hindering studies on content moderation, algorithms, and systemic risks.
The DSA claims this penalty is relatively modest, signaling an initial warning – but plans to fine billions more if X is non-compliant.
New word for the day: OVERVAXXER
Words matter: So let’s reach consensus on a concise definition of overvaxxer to include in a dictionary, and then work get it into the lexicon of everyday Americans.
Overvaxxer Derangement Syndrome (ODS)
ODS pronunciation: /ō′dē-əs/
extra points for those that understand the meaning of “double entendre”. Double extra points for those that understand why this is relevant.
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As many people are not following carefully what is happening with the fraud cases (and there are many) in Minnesota, an explanation is in order.
The fraud case surrounding Tim Walz centers on his administration’s failure to provide basic oversight of Minnesota’s Feeding Our Future (FOF) program, which fostered one of the largest welfare fraud scandals in U.S. history and resulted in more than $250 million in losses from fake child-nutrition claims.
Walz’s leadership allowed politically connected nonprofits, which are associated with the Somali community in that state, to siphon taxpayer dollars with virtually no accountability, even after repeated warnings from whistleblowers and state officials. Rather than intervening early, Walz’s agencies deferred responsibility, blamed federal bureaucratic constraints, and failed to stop the fraud until the FBI stepped in. This is evidence of systemic mismanagement and of a broader pattern in which Democratic administrations.
At best, Minnesota Governor Walz’s administration hesitated to oversee the program properly because FOF and its affiliates were connected to a protected political group, namely Somali-American nonprofits and businesses. The fraudsters took advantage of the situation, knowing that the use of racial-equity language and fears of discrimination accusations made state agencies less likely to audit immigrant-operated sites.
Furthermore, this immigrant population is concentrated in specific congressional districts, specifically MN-CD-5. It appears that at some level, Governor Walz knew about this fraud and allowed it to happen because he wanted the votes of the Somali-Americans and to ensure that Congressman Ilhan Omar remains in power. The current congressional representative for Minnesota’s 5th Congressional District (MN-CD-5) is Ilhan Omar.
The implications of this are profound. It would be a crime if Gov. Walz and Congressman Ilhan Omar aided and abetted this fraud. Certainly, Ilhan Omar and her staff knew many of those now indicted, and at least two of her staff are implicated. Time will tell whether there is a crime at the highest levels of Minnesota governance.
The Federal government is now heavily involved in the investigation.
The left is getting triggered by MAGA people calling Tim Walz a retard – and I must say, watching the red-faced liberals get overwrought over the word “retard” is kind of funny.
Honestly, we need a slur for people who use artificial intelligence for everything.
Never forget, a Venn diagram can demonstrate correlation, but not causation.
Watching Adam Rose is like watching a slow-moving train wreck. As much as you want to avert your eyes, you just can’t…
This Christmas, remember that made in America is best!
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Let’s have a little fun at the expense of one of our favorite politicians!
POLL
Who would vote for Gov. Newsom for President in 2028?
Not over my dead body
He is God’s gift to America
245 VOTES · 23 HOURS REMAINING
Today’s livestreaming of the CDC ACIP meeting below:
Dr. Frances Oldham Kelsey was born on Vancouver Island in 1914, in a small fishing village called Cobble Hill. Her childhood was not one of privilege, but it is said that she threw herself into reading, with a curiosity that could not be contained.
Kelsey won admission to McGill University, where she studied pharmacology. She graduated with honors and was quickly recognized by leading researchers for her meticulous attention to detail.
In the 1930s, discrimination was so baked into academia that when McGill professor E.M.K. Geiling requested a new graduate assistant, the university, assuming “Frances” was a man, sent her name. He was surprised when she arrived, but her work ethic won him over. With Geiling she helped investigate a series of tragic deaths linked to a toxic solvent in a sulfanilamide drug formulation, an early experience that shaped her lifelong insistence on drug safety.
She earned her Ph.D. in 1938 at the University of Chicago, and then a a degree in medicine in 1950, making her a dual-trained physician-pharmacologist.
The Call From Washington
In 1960, at age 45, Kelsey applied for a medical officer position at the U.S. Food and Drug Administration. The FDA also assumed that “Frances” was a man. But they quickly learned that she was, as one coworker later said, “the toughest reviewer in the place.”
Her very first major assignment seemed routine. She was to review a new sedative widely marketed in Europe for anti-nausea in pregnancy. The drug was called thalidomide, and the review was considered a formality for approval in the United States.
The Woman Who Said No
Kelsey refused to sign off.
She noticed details that others ignored:
The company had not provided rigorous U.S. clinical trial data.
Peripheral neuropathy was showing up in European patients.
Animal studies were incomplete.
Most importantly, no one had tested it for effects on pregnancy, despite its heavy use by pregnant women.
By regulation, she could defer approval for thirty days. So as each month rolled around, she put in another deferral. For a new employee, this was a radical thing to do.
For months, the drug company pressured her: phone calls, letters, meetings, repeated complaints to her supervisors. But Kelsey held firm. She had seen what rushed approvals could do. Something about thalidomide felt wrong.
Then, in late 1961, what she feared became a reality: reports poured in from Europe and Australia of babies born with catastrophic limb deformities, a condition called phocomelia, after their mothers took thalidomide early in pregnancy.
National Recognition Came Swiftly
In 1962 President John F. Kennedy awarded her the President’s Award for Distinguished Federal Civilian Service, one of the highest honors a civilian can receive. Kennedy praised her refusal to bow to commercial pressure and noted that her actions had saved countless families from heartbreak.
Her work also triggered the passage of the 1962 Kefauver-Harris Amendments, which transformed the FDA and made modern drug regulation possible: requiring proof of safety and efficacy, informed consent in clinical trials, and strict oversight of advertising claims.
Unfortunately, this act was diluted by the 1997 FDA Modernization Act (FDAMA) which paved the way for modern advertising, by allowing more direct-to-consumer (DTC) broadcast ads.
A Lifelong Career in Drug Safety
Kelsey continued her work at the FDA for many decades. She led the new drug evaluation office, mentored younger scientists, and remained a fierce advocate for evidence-based medicine.
Even in her 80s, she was still teaching and reviewing cases. At age 90, she retired.
Frances Kelsey lived to be 101. She died in 2015, just two weeks after the Canadian government formally recognized her as a national hero. It only took the Canadian government 55 years to recognize her accomplishments. During her long career, she never received the Nobel Prize in Medicine, as that is reserved for discovering something new, rather than preventing harm.
She never sought fame. She never cashed in her story. She remained, throughout her life, a scientist committed to one principle: patients deserve protection, not assumptions. That informed consent is paramount for patient’s right.
So, remember to stand up and defend what is right – even in the face of tyranny. And never forget that famous Thomas Jefferson quote:
Image of Bohmite, the mineral version of the common Aluminum vaccine adjuvant known as Alum. Chemically, the crystalline aluminum oxyhydroxide AIOOH. The structure consists of corrugated sheets of aluminum octahedra.
Are all vaccines similar, and what ingredients are in vaccines?
Each approved vaccine is a unique mixture of both ingredients and manufacturing processes. From a regulatory standpoint, vaccine products are a combination of ingredients, manufacturing process, process controls (including release testing), and supporting safety and efficacy/effectiveness testing. The repeated assertion that all vaccines are safe and effective is mere propaganda. Each licensed vaccine product has its own profile of risks, benefits, pharmacology, immunology, and other characteristics.
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For the sake of discussion, vaccine products can be divided into three general categories.
Live Vaccines
Classically, “live” vaccines are essentially replication-competent viruses, bacteria, or potentially other replication-competent biological material. Simple examples include the oral polio vaccine, the yellow fever vaccine, the smallpox vaccine, and the Tuberculosis vaccine (BCG). A more recent example of this category is the “Flumist” influenza virus vaccine. In all of these cases, the patient is offered a product that actually infects them in some way, but – assuming that they have a “normal” properly functioning immune system – will not cause clinical disease. If the patient is immunosuppressed in some way, all bets are off. In the case of “live” vaccines, dosage, purity, identity, and “titer” of the product are critical. To illustrate this with a simple example, if you take multiple doses of yellow fever vaccine in close succession, you will get clinical yellow fever, and it can kill you. In general, “live” vaccines are the most effective, as they most closely mimic actual infection by a pathogen. However, they do cause the cells and tissues of your body to actually manufacture foreign proteins, similar to gene therapy-based vaccines.
Dead Vaccines.
“Dead” vaccines were originally prepared by taking a “live” replication-competent agent (virus or bacteria), growing it in some sort of material that will support replication (fermentation broth, cell culture, or fertile/embryonated chicken eggs for example) and “killing” or inactivating it in some way, typically by adding a chemical that would either break up the agent into its components, or damage its genome so that it could no longer replicate. One major problem with these types of products is purity, as this category is prone to contamination coming from the material used to support replication of the pathogen. The early anthrax vaccines used by the US Military during “Desert Storm” were notoriously “dirty” or contaminated with material that had nothing to do with the parts of the killed anthrax that were intended to be included in the product. Over time, various methods have been developed to produce much purer “antigens” or immunogenic components (including the use of recombinant DNA together with fermentation and advanced purification technology), but the paradox has been that as the preparations became purer, their “immunogenicity” was reduced. Essentially, the impurities were biologically active and often increased the adaptive (and innate) immune response to the intended “antigen” from the pathogen. This relates to the topic at hand, that being the use of “adjuvants” in vaccines. A related point is that, in the case of modern “subunit” vaccines produced using recombinant DNA technology, the biologically active “antigen” is produced outside your body and then injected. This is very different from the next and newest category of vaccines and technologies.
Gene Therapy-based Vaccines
The newest (third) category involves the use of recombinant DNA and/or gene therapy technologies to cause your body to manufacture some part of a pathogen, which, when presented to your immune system by your own cells, causes your body to mount an immune response (innate and/or adaptive) to the foreign protein derived from a pathogen. In many ways, this is similar to the first category, live attenuated vaccines. In the case of live attenuated vaccines, a weakened version of the pathogen is injected (or swallowed) and it replicates in your body. In the case of gene therapy-based vaccines, either a recombinant virus (such as an adenovirus) or a non-viral gene delivery formulation (mod mRNA or DNA) is administered, and this causes your body to produce a part of the pathogen (such as the spike protein from SARS-CoV-2). Another variant of this involves engineering the vesiculovirus (VSV) to display an Ebola virus protein on its surface – this is the Merck VSV Ebola vaccine. In that case, the VSV acts both as a gene therapy vector producing a specific adaptive immune response to Ebola, and also triggers a strong innate immune response. Up for discussion in that case is which is the more important active component. The latest version of gene therapy tech used for vaccination involves self-replicating RNA vectors based on alphaviruses.
In the case of the lipid nanoparticle-delivered mod mRNA vaccines, the inclusion of small DNA fragments derived from the bacterial DNA used to make the mod mRNA is probably a form of an adjuvant, much like other adjuvants commonly used with “killed” vaccines.
Adjuvants and Vaccines
What is an adjuvant? Quite simply, a vaccine adjuvant is any substance or compound added to a vaccine to enhance the body’s immune response to the antigen (the part of the vaccine that mimics the pathogen). This broad definition underscores the “anything goes” nature of adjuvants. You can find a pretty comprehensive list of known adjuvants here. This list was compiled by vaccine experts from both DoD and NIH/NIAID who were friends of mine, back in the days when I was very involved in AIDS vaccine development. It used to be available for download on the NIH website, but has since been removed. Fortunately, I kept a copy and have now made it available for downloading. It is a bit dated, but still represents the most comprehensive summary of adjuvants that I am aware of.
Adjuvants are used by researchers and the vaccine industry to stimulate adaptive immune responses to pathogen-specific antigens. At a simplistic level, you can think of an adjuvant as something that provides a “danger signal” to the immune system, causing it to respond to a foreign molecule when it otherwise might not respond. Typical adjuvants act to increase the strength and duration of the immune response, allow lower doses of antigen to be effective (dose-sparing), broaden the immune response (e.g., against drifting viral strains), direct the type of immune response (e.g., favor antibody production or T-cell activation), and improve overall vaccine efficacy in populations with weaker responses (infants, elderly, immunocompromised).
As discussed above regarding the category of “dead” vaccines, industry experience has been that, in general, the more pure the vaccine antigen, the less active it is for eliciting a robust adaptive (B and T cell) immune response. In other words, An adjuvant is an immune-response “booster” deliberately included in some vaccines to make them work better.
General categories of adjuvants include the following:
Aluminum salts (alum) – oldest and most widely used (in many childhood vaccines like DTaP, hepatitis B)
Oil-in-water emulsions – e.g., MF59 (in some flu vaccines for elderly), AS03 (in pandemic flu vaccines)
Liposome-based – e.g., AS01 (in Shingrix shingles vaccine and some malaria vaccines)
TLR agonists – e.g., CpG 1018 (in Heplisav-B hepatitis B vaccine), MPL (in Shingrix)
Saponin-based – e.g., QS-21 (in Shingrix and some COVID/malaria vaccines)
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Various forms and formulations of aluminum salts are used as vaccine adjuvants. These preparations are among the oldest and most widely used adjuvants. These are NOT the same as powdered metallic aluminum or free aluminum ions, which ARE highly toxic to humans.
Almost every inactivated or subunit vaccine given to infants and young children contains aluminum (except pneumococcal conjugates and Hib PedvaxHIB).
Many novel or experimental adjuvants employ aluminum salts together with other agents (liposomes etc.)
Most live vaccines and modern conjugate/mod mRNA vaccines do not contain aluminum.
Clinical Syndromes associated with aluminum powder, aluminum ion or injected aluminum exposure toxicity include
Dialysis encephalopathy (dialytic dementia)
Caused by high aluminum in dialysis fluid pre-1980s
Now extremely rare due to water treatment standards
Parenteral Neonatal (PN) Aluminum Toxicity
Preterm infants exposed to 4–5 μg/kg/day IV aluminum via parenteral nutrition show neurodevelopmental and bone toxicity.
These findings led to FDA aluminum limits for parenteral nutrition solutions.
Vaccine-day aluminum doses, although differing in chemical structure from free aluminum ions, can be orders of magnitude higher per kg than PN limits.
Aluminum-induced bone disease (osteomalacia)
Seen in long-term parenteral nutrition or dialysis patients
Fracturing bone pain, hypercalcemia, resistance to vitamin D
Pulmonary fibrosis / aluminosis
From chronic intense inhalation of aluminum powder
Rare occupational disease
Macrophagic myofasciitis (MMF)
Persistent aluminum-containing granulomas at intramuscular injection sites (mostly deltoid)
Symptoms in many MMF patients: chronic myalgias, fatigue, and cognitive difficulties.
Detected in some patients with myalgia, fatigue, and cognitive issues
Causal link to systemic symptoms is not universally accepted
Muscle biopsies show aluminum-loaded macrophages (MMF lesions) at prior vaccine sites years later. This demonstrates long-term persistence of aluminum adjuvants in human tissue.
ccross-posted a post from 
Dr. Robert W. Malone Dec 8 · Malone News
